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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOLC1 All Species: 25.76
Human Site: S622 Identified Species: 43.59
UniProt: Q14978 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14978 NP_004732.2 699 73603 S622 K K G E K R A S S P F R R V R
Chimpanzee Pan troglodytes XP_001171017 700 73581 S623 K K G E K R A S S P F R R V R
Rhesus Macaque Macaca mulatta XP_001112196 701 73703 S624 K K G E K R A S S P F R R V R
Dog Lupus familis XP_851848 704 74723 S627 K K G E K R A S S P F R R I R
Cat Felis silvestris
Mouse Mus musculus O08784 1320 134983 G1197 L S G D L E A G A P K N K K K
Rat Rattus norvegicus P41777 704 73545 S627 K K G E K R A S S P F R R V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511079 669 69188 S569 K K A E R R A S S P F R R V R
Chicken Gallus gallus XP_421630 694 72200 S617 V P K V K R A S S P F R R V R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689627 1001 102013 N924 R T K Q K D S N A P F R R I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730693 686 70584 R611 S G G G S G R R S P F R R V R
Honey Bee Apis mellifera XP_001120943 685 75016 N609 N N D K Q P K N T P F R R V K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796224 791 84162 N714 M K K G R K S N E P F R R V K
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001168628 517 55362 R448 R I K V D D V R F A D D R L Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32583 406 40997 R337 G Q R K H F S R V D R S K I N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 94.2 81.5 N.A. 24.9 74.1 N.A. 50.7 43.6 N.A. 36.6 N.A. 27.3 22 N.A. 34.5
Protein Similarity: 100 98.8 95.5 85.6 N.A. 36.7 81.2 N.A. 60.3 57.5 N.A. 47.5 N.A. 42.3 42.9 N.A. 47.9
P-Site Identity: 100 100 100 93.3 N.A. 20 100 N.A. 86.6 73.3 N.A. 40 N.A. 53.3 33.3 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 46.6 100 N.A. 93.3 73.3 N.A. 80 N.A. 53.3 66.6 N.A. 73.3
Percent
Protein Identity: N.A. 23.6 N.A. N.A. 25.1 N.A.
Protein Similarity: N.A. 40.9 N.A. N.A. 39.4 N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. 0 N.A.
P-Site Similarity: N.A. 26.6 N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 58 0 15 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 8 15 0 0 0 8 8 8 0 0 0 % D
% Glu: 0 0 0 43 0 8 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 8 0 79 0 0 0 0 % F
% Gly: 8 8 50 15 0 8 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 0 22 0 % I
% Lys: 43 50 29 15 50 8 8 0 0 0 8 0 15 8 22 % K
% Leu: 8 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 0 0 0 0 0 22 0 0 0 8 0 0 8 % N
% Pro: 0 8 0 0 0 8 0 0 0 86 0 0 0 0 0 % P
% Gln: 0 8 0 8 8 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 15 0 8 0 15 50 8 22 0 0 8 79 86 0 65 % R
% Ser: 8 8 0 0 8 0 22 50 58 0 0 8 0 0 0 % S
% Thr: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % T
% Val: 8 0 0 15 0 0 8 0 8 0 0 0 0 65 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _